Copper Tripeptide-1 CAS 89030-95-5

Blue Copper Peptide | Copper Tripeptide-1 CAS 89030-95-5 | Tripeptide-1 Copper | Cosmetic Ingredients | Kilogram Supply | Science-Peptide

Blue Copper Peptide (GHK-Cu)--Anti-aging and repairing cosmetic peptide, promotes collagen regeneration and repairs the barrier.Science-Peptide provides high purity Blue Copper Peptide, supporting the supply of kilograms, with good stability, suitable for serums, creams, lyophilized powders and other formulations. Welcome to inquire.

Blue copper peptide, also known asCopper Tripeptide-1 CAS 89030-95-5 (GHK-Cu), in the cosmetics industry is considered to be the "old-timer". Since its discovery in 1973, it has been used in skin care products for almost fifty years. After so many years, new peptides come and go, but the blue copper peptide has not been eliminated, relying on real skills - it can promote collagen regeneration, but also repair the skin barrier, but also with the antioxidant function of copper ions, a molecule to do several things.

 

We have been in the field of peptide synthesis for 20 years, blue copper peptide is our regular species, mature technology, stable quality, can be a stable supply of kilograms. Compared with those long peptides with 20 to 30 amino acids, blue copper peptide has only three amino acids, so it is good to do, but to achieve stable batch to batch, the color is consistent, and suitable for cosmetic formulations, it also has its own way.

The INCI name for the blue copper peptide is Copper Tripeptide-1 CAS 89030-95-5, and the chemical structure is GHK-Cu--glycyl-histidyl-lysine, which is then complexed with a copper ion. The three amino acids are arranged in a row with a copper ion in the middle. The structure looks simple, but it's quite versatile:

Promotes collagen: It stimulates fibroblasts to synthesize collagen, elastin, and glycosaminoglycans for firmer, more elastic skin.
Barrier Repair: Accelerates skin barrier repair and reduces transdermal water loss.
Anti-inflammatory and antioxidant: Copper ions have their own antioxidant activity and also reduce inflammatory factors, making them friendly to sensitive skin.
Promotes Wound Healing: This discovery was first made in wound healing research and is now used in medical aftercare products.

In cosmetic formulations, blue copper peptides are commonly found in:
Anti-aging serum/cream: focuses on firming, lightening lines, and improving sagging
Repairing products: sensitive skin, barrier damage, post-medical repair
Lyophilized powder/liquid: high concentration of blue copper peptide products, the main intensive repair
Its reputation among consumers is also quite loud. The word "blue copper peptide" itself carries the label of "high-end anti-aging", and many brands promote it as a main ingredient.

1. Stable supply of kilogram-scale capacity
Blue copper peptide in cosmetics is not a small amount, a pop-up products may use up dozens of kilograms a month. We amplify the process run through, can be a stable supply of kilograms of products. You use dozens of kilograms a month, we can also catch, constantly supply.

2. Stable color, consistent from batch to batch
Blue copper peptide is blue in color, which is determined by copper ions. However, whether this blue color can be maintained between different batches is a test of technology. We strictly control the complexation conditions and purity to ensure that the color of each batch of products is uniform, and there will not be a batch of dark blue and a batch of light blue. Formulators are most afraid of color fluctuations, and can't even adjust the color back.

3. Sufficiently pure and low in impurities
The impurities in blue copper peptides are mainly free peptides and free copper ions that are not complexed. The free peptide has no effect and the free copper ion may irritate the skin. We do a good job of purification, measuring the purity of each batch (HPLC), free copper ions are also controlled within the safe range. Regular purity ≥98%, free copper ion <0.5%.

4. Good adaptability of formulations
Blue copper peptide has good water solubility, it can be dissolved in pure water, propylene glycol and butylene glycol. However, it has a temperament - it is afraid of chelating agents, such as disodium EDTA, citric acid, etc. These chelating agents will take away the copper ions and inactivate the blue copper peptide. We will remind the formulators to pay attention to this in TDS. If you know its temperament, you can use it well.

5. Complete documentation
Provide COA report (purity, moisture, appearance, free copper), MS profile, HPLC profile, TDS, MSDS. stability data can also be provided if needed.

Blue Copper Peptide is not a niche ingredient, it is used by many international brands and Chinese leading brands. The formulators chose it not because the concept is new, but because the efficacy is stable.

1. NIOD Blue Copper Peptide Extract (Canada)
Deciem's NIOD, there is a "Copper Amino Isolate Serum", focusing on high concentration of blue copper peptide, with more than a dozen kinds of amino acids and peptides. The price is not cheap, 30ml sells several hundred, but in the ingredient party circle reputation is very good. Its formula idea is a high concentration of blue copper peptide + multi-repeat distribution, take the "fierce medicine" route.

2. Drunk Elephant Blue Copper Peptide Cream (United States)
Drunk Elephant's "Protini Polypeptide Cream" contains blue copper peptide, signaling peptide and growth factor, focusing on peptide anti-aging. This product sells well at Sephora and is one of Drunken Elephant's star products. It combines blue copper peptide with other peptides, which means that blue copper peptide is actually very good - as long as you avoid chelating agents.

3. Peter Thomas Roth Petrov Blue Copper Peptide Extract (United States)
Petrov has a "Copper Peptide Complex", focusing on high concentration of blue copper peptide + a variety of ceramides, repair and anti-aging both. It's a high-end line route, the price is not low, but it's been sold in beauty salons and high-end department stores for many years.

4. Perrier Blue Copper Peptide Repair Essence (China)
In the national product Perrier is an early push blue copper peptide. Their "Blue Copper Peptide Repair Essence" focuses on sensitive skin repair, adding not low, but also with repair ingredients, in the small red book on the high degree of heat. The formula specifically avoids EDTA and carbomer, indicating that they do their homework very carefully.

5. Marumi Blue Copper Peptide Firming Eye Cream (China)
Marumi is to do eye care started, their blue copper peptide eye cream focus on firming and light lines, the formula also added dipeptide-2 to go to the swelling, is the eye cream is more classic compounding ideas.

Blue copper peptide is good, but it has a "temperament": it is afraid of chelating agents.
Disodium EDTA, citric acid, phytic acid, these chelating agents, the blue copper peptide in the copper ions "rob", so that the blue copper peptide into free peptide + free copper. Free peptide has no effect, and free copper may also irritate the skin. Therefore, if there is blue copper peptide in the formula, do not add chelating agent, or put the blue copper peptide in the last step to reduce the contact time.
In addition, the stability of blue copper peptide will be reduced under acidic conditions, so it is best to control the pH of the formula between 5.5-7.0. These precautions will be clearly written in the TDS to help formulators to step on the pitfalls less.

Blue copper peptide is the classic type of cosmetic peptide, which has not been eliminated for 50 years, relying on the real efficacy. We have been doing peptides for 20 years, and we have mature technology, stable quality, and no problem in supplying kilograms of blue copper peptide, which is a classic species. If you are doing anti-aging serum, repair cream, and need a stable supplier of blue copper peptide, welcome to talk to us.